Matthew A Brown Selected Research

Arthritis (Polyarthritis)

1/2021	Inflammasome Activation in Ankylosing Spondylitis Is Associated With Gut Dysbiosis.
1/2020	Epistatic interactions between killer immunoglobulin-like receptors and human leukocyte antigen ligands are associated with ankylosing spondylitis.
1/2020	Whole-Exome Sequencing Reveals a Rare Missense Variant in SLC16A9 in a Pedigree with Early-Onset Gout.
1/2017	Early anti-inflammatory intervention ameliorates axial disease in the proteoglycan-induced spondylitis mouse model of ankylosing spondylitis.
5/2015	Major histocompatibility complex associations of ankylosing spondylitis are complex and involve further epistasis with ERAP1.
7/2014	Interleukin-23 mediates the intestinal response to microbial β-1,3-glucan and the development of spondyloarthritis pathology in SKG mice.
1/2013	The role of IL-17-secreting mast cells in inflammatory joint disease.
7/2012	β-glucan triggers spondylarthritis and Crohn's disease-like ileitis in SKG mice.
1/2005	Antibody treatments of inflammatory arthritis.

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Matthew A Brown Research Topics

Disease

36	Ankylosing Spondylitis 04/2022 - 10/2004
13	Inflammation (Inflammations) 01/2020 - 01/2005
11	Rheumatoid Arthritis 11/2017 - 09/2002
9	Arthritis (Polyarthritis) 01/2021 - 01/2005
7	Psoriasis (Pustulosis Palmaris et Plantaris) 01/2022 - 11/2010
6	Axial Spondyloarthritis 01/2022 - 08/2012
6	Necrosis 01/2022 - 11/2015
6	Spondylitis 01/2019 - 07/2012
6	Chondrocalcinosis (Pseudogout) 01/2017 - 10/2002
5	Osteoporosis 01/2020 - 03/2005
5	Inflammatory Bowel Diseases (Inflammatory Bowel Disease) 01/2019 - 06/2002
5	Neoplasms (Cancer) 11/2018 - 10/2012
4	Non-Radiographic Axial Spondyloarthritis 01/2022 - 06/2013
4	Crohn Disease (Crohn's Disease) 01/2021 - 06/2002
4	Disease Progression 01/2017 - 03/2011
4	Joint Diseases (Joint Disease) 06/2014 - 04/2006
3	Genetic Risk Score 04/2022 - 01/2020
3	Sacroiliitis 01/2022 - 01/2018
3	Hypertension (High Blood Pressure) 01/2022 - 01/2020
3	Type 2 Diabetes Mellitus (MODY) 01/2021 - 02/2011
3	Back Pain (Backache) 01/2021 - 06/2013
3	Ileitis 01/2021 - 07/2012
3	Spondylarthropathies 01/2020 - 04/2015
3	Disease Susceptibility (Diathesis) 01/2019 - 02/2010
3	Genetic Predisposition to Disease (Genetic Predisposition) 08/2016 - 09/2002
3	Multiple Sclerosis 10/2010 - 03/2010
2	Systemic Scleroderma (Systemic Sclerosis) 06/2022 - 01/2021
2	Autoimmune Diseases (Autoimmune Disease) 06/2022 - 01/2019
2	Uveitis 01/2022 - 07/2012
2	Hemorrhage 10/2021 - 01/2021
2	Dysbiosis 01/2021 - 10/2020
2	Adenocarcinoma 01/2021 - 10/2012
2	Hypertrophy 01/2021 - 04/2005
2	Heart Failure 01/2021 - 01/2020
2	Nevus (Nevi) 01/2019 - 11/2018
2	Melanoma (Melanoma, Malignant) 01/2019 - 11/2018
2	Pain (Aches) 01/2018 - 03/2014
2	Immune System Diseases (Immune Disorders) 01/2018 - 01/2016
2	Calcinosis 01/2015 - 01/2012
2	Asthma (Bronchial Asthma) 06/2014 - 09/2011
2	Osteoarthritis 12/2013 - 02/2012
2	Jeune syndrome 11/2013 - 11/2013
2	Ciliopathies 11/2013 - 11/2013
2	Ankylosis 11/2012 - 01/2012
2	Spondylarthritis (Spinal Arthritis) 07/2012 - 06/2002
2	Myositis Ossificans (Fibrodysplasia Ossificans Progressiva) 03/2011 - 05/2006

Drug/Important Bio-Agent (IBA)

14	Proteins (Proteins, Gene)FDA Link 01/2020 - 10/2002
9	HLA-B27 Antigen (HLA B27 Antigen)IBA 04/2022 - 07/2011
8	HLA-B Antigens (HLA-B)IBA 01/2020 - 09/2011
7	Biological ProductsIBA 01/2022 - 02/2014
7	C-Reactive ProteinIBA 01/2021 - 01/2009
7	HLA-DRB1 Chains (HLA DRB1)IBA 01/2019 - 01/2003
6	HLA Antigens (Human Leukocyte Antigens)IBA 01/2022 - 10/2010
6	Interleukin-23 (Interleukin 23)IBA 01/2022 - 04/2009
6	Biomarkers (Surrogate Marker)IBA 01/2020 - 02/2012
6	Ethylnitrosourea (N-Ethyl-N-nitrosourea)IBA 01/2019 - 01/2012
5	CytokinesIBA 01/2017 - 01/2005
5	diphosphoric acid (pyrophosphoric acid)IBA 01/2012 - 04/2005
4	DNA (Deoxyribonucleic Acid)IBA 04/2022 - 08/2007
4	Tumor Necrosis Factor InhibitorsIBA 01/2022 - 01/2014
4	InterleukinsIBA 01/2022 - 02/2010
4	AntigensIBA 01/2020 - 01/2007
4	AminopeptidasesIBA 01/2018 - 07/2011
4	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 01/2018 - 01/2003
4	Amino Acids FDA Link 10/2017 - 12/2014
4	Proteoglycans (Proteoglycan)IBA 01/2017 - 11/2012
4	Peptides (Polypeptides)IBA 01/2015 - 07/2011
3	Interleukin-17 (Interleukin 17)IBA 01/2022 - 01/2013
3	AutoantibodiesIBA 01/2021 - 01/2009
3	curdlanIBA 01/2021 - 07/2012
3	Pharmaceutical PreparationsIBA 11/2020 - 02/2014
3	HLA-C Antigens (HLA-C)IBA 01/2019 - 11/2010
3	Calcium PyrophosphateIBA 01/2017 - 10/2002
3	RNA (Ribonucleic Acid)IBA 12/2013 - 03/2011
3	Interleukin-1 (Interleukin 1)IBA 01/2013 - 10/2004
3	EnzymesIBA 01/2013 - 05/2011
2	Methotrexate (Mexate)FDA LinkGeneric 01/2022 - 09/2021
2	Non-Steroidal Anti-Inflammatory Agents (NSAIDs)IBA 11/2020 - 06/2013
2	HLA-A Antigens (HLA-A)IBA 10/2020 - 01/2019
2	EpitopesIBA 01/2020 - 04/2014
2	Uric Acid (Urate)IBA 01/2020 - 01/2011
2	Untranslated RNA (Noncoding RNA)IBA 01/2020 - 06/2016
2	LigandsIBA 01/2020 - 01/2009
2	T-Cell Antigen Receptors (T-Cell Receptor)IBA 01/2020 - 07/2012
2	Fibrillin-1IBA 01/2020 - 01/2016
2	micaIBA 01/2020 - 11/2018
2	HLA-DPB1 antigen (HLA DPB1)IBA 01/2019 - 10/2010
2	Leukocyte L1 Antigen Complex (Calgranulin)IBA 01/2018 - 01/2009
2	Aligeron (AS 2)IBA 01/2018 - 04/2005
2	Serine (L-Serine)FDA Link 10/2017 - 03/2011
2	Interleukin-6 (Interleukin 6)IBA 11/2015 - 01/2013
2	Phosphates (Orthophosphate)IBA 01/2015 - 04/2012
2	P-2 (P 2)IBA 06/2014 - 01/2013
2	Initiator Codon (Start Codon)IBA 03/2014 - 04/2005
2	Adrenal Cortex Hormones (Corticosteroids)IBA 03/2014 - 01/2005
2	OsteocalcinIBA 03/2014 - 11/2012

Therapy/Procedure

13	Therapeutics 01/2021 - 01/2005
3	Transjugular Intrahepatic Portasystemic Shunt 10/2021 - 02/2020
3	Surgical Portasystemic Shunt (Portosystemic Shunt) 10/2021 - 02/2020
2	Endurance Training 01/2022 - 01/2021